HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloropropanesulphonyl chloride → Ethyl 6-(1,1-dioxo-1lambda6-isothiazolidin-2-yl)nicotinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloropropanesulphonyl chloride | HCID 15410 | — |
| Reactant | Ethyl 6-Aminonicotinate | HCID 235927 | — |
| Product | Ethyl 6-(1,1-dioxo-1lambda6-isothiazolidin-2-yl)nicotinate | HCID 71251937 | — |
Reaction Steps
Using ethyl 6-aminonicotinate (2.02 g) and 3-chloropropane-1-sulfonyl chloride (1.8 mL) and by the reaction and treatment in the same manner as in Preparation Example 17, the title compound (2.29 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-053c09d130f14d83a6605e3e02a66ae6 |
| Source note | uspto-grants-2014_08 |