HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2,4-Xylyl)piperazine → (4-Bromo-2-fluorophenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2,4-Xylyl)piperazine | HCID 70544 | — |
| Reactant | 4-Bromo-2-fluorobenzoic acid | HCID 302681 | — |
| Product | (4-Bromo-2-fluorophenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone | HCID 58484705 | 100.8% |
Reaction Steps
Using 4-bromo-2-fluorobenzoic acid (5 g) and 1-(2,4-dimethylphenyl)piperazine (4.4 g) and by the reaction and treatment in the same manner as in Preparation Example 109, the title compound (9 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-5f9cb00d842e44e0962bdd0bb478d81c |
| Source note | uspto-grants-2014_08 |