HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodobenzoyl chloride → [4-(5-Ethyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodobenzoyl chloride | HCID 74373 | — |
| Reactant | 1-(5-Ethyl-3-methylpyridin-2-yl)piperazine | HCID 58484578 | — |
| Product | [4-(5-Ethyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone | HCID 58484605 | 90.5% |
Reaction Steps
Using 1-(5-ethyl-3-methylpyridin-2-yl)piperazine (2.46 g) described in Preparation Example 81 and 4-iodobenzoyl chloride (3.36 g) and by the reaction and treatment in the same manner as in Preparation Example 108, the title compound (4.72 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-f586afa178084685aaac472a456578e9 |
| Source note | uspto-grants-2014_08 |