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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411299Generated: October 30, 2026

2-Fluoro-4-iodobenzoic acid → HCID 71251867, compound

https://huagongshe.com/reaction/2411299

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-iodobenzoic acidHCID 2774516—
Reactant1-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine hydrochlorideHCID 67381091—
ProductHCID 71251867HCID 7125186795.8%

Reaction Steps

Using 2-fluoro-4-iodobenzoic acid (399 mg) and 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine hydrochloride (381 mg) described in Preparation Example 82 and by the reaction and treatment in the same manner as in Preparation Example 160, the title compound (668.5 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-683f3d96dece45a9a3539ded5cf293a8
Source noteuspto-grants-2014_08