HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2,4-Xylyl)piperazine → (4-Bromo-3-chlorophenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2,4-Xylyl)piperazine | HCID 70544 | — |
| Reactant | 4-Bromo-3-chlorobenzoic acid | HCID 12594302 | — |
| Product | (4-Bromo-3-chlorophenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone | HCID 58484864 | 100.7% |
Reaction Steps
Using 4-bromo-3-chlorobenzoic acid (2.4 g) and 1-(2,4-dimethylphenyl)piperazine (1.9 g) and by the reaction and treatment in the same manner as in Preparation Example 109, the title compound (4.1 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-32f3b19ad40745bd96c4b60a3039bff9 |
| Source note | uspto-grants-2014_08 |