HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dibromobenzoic acid → [4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](2,4-dibromophenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dibromobenzoic acid | HCID 11896 | — |
| Reactant | 1-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine | HCID 58484718 | — |
| Product | [4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](2,4-dibromophenyl)methanone | HCID 71252039 | 69.4% |
Reaction Steps
Using 2,4-dibromobenzoic acid (530 mg) and 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine (413 mg) described in Preparation Example 83 and by the reaction and treatment in the same manner as in Preparation Example 118, the title compound (630 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-454dbf25e8c64176a8b60eaa061ad254 |
| Source note | uspto-grants-2014_08 |