HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dimethyl-2,4-Imidazolidinedione → Methyl 6-(3,5-dimethyl-2,4-dioxoimidazolidin-1-yl)-2-methylnicotinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dimethyl-2,4-Imidazolidinedione | HCID 10154061 | — |
| Reactant | Methyl 6-bromo-2-methylpyridine-3-carboxylate | HCID 71691566 | — |
| Product | Methyl 6-(3,5-dimethyl-2,4-dioxoimidazolidin-1-yl)-2-methylnicotinate | HCID 71252642 | 16.4% |
Reaction Steps
Using methyl 6-bromo-2-methylnicotinate (96 mg) and 3,5-dimethylimidazolidine-2,4-dione (107 mg) described in Preparation Example 217 and by the reaction and treatment in the same manner as in Preparation Example 48, the title compound (19 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-c55045bd276a4ea2bea0320410589f0a |
| Source note | uspto-grants-2014_08 |