HuagongsheHuagongshe Chemistry Print Report · For research reference only
[4-(3,5-Dimethylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone → HCID 71253082, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [4-(3,5-Dimethylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone | HCID 58484535 | — |
| Reactant | HCID 86676750 | HCID 86676750 | — |
| Product | HCID 71253082 | HCID 71253082 | 12.9% |
Reaction Steps
Using (R)-3-ethylisothiazolidine 1,1-dioxide (150 mg) described in Preparation Example 3 and [4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone (421 mg) described in Preparation Example 113 and by the reaction and treatment in the same manner as in Example 1, the title compound (57 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-bfbd4945fcde464685b19661fcd24763 |
| Source note | uspto-grants-2014_08 |