[4-(3,5-Dimethylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone → (S)-[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl][4-(4-methyl-1,1-dioxo-1lambda6-isothiazolidin-2-yl)phenyl]methanone

Participants

Reaction Steps

Using [4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone (130 mg) described in Preparation Example 113 and (S)-4-methylisothiazolidine 1,1-dioxide (84 mg) described in Preparation Example 4 and by the reaction and treatment in the same manner as in Example 1, the title compound (32 mg) was obtained.

Provenance & Evidence