HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 16664117, compound → HCID 71252414, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 16664117 | HCID 16664117 | — |
| Reactant | (4-Bromo-2-fluorophenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone | HCID 58484705 | — |
| Product | HCID 71252414 | HCID 71252414 | 60.5% |
Reaction Steps
Using (S)-3-benzyloxymethylisothiazolidine 1,1-dioxide (536 mg) described in Preparation Example 1 and (4-bromo-2-fluorophenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone (869 mg) described in Preparation Example 116 and by the reaction and treatment in the same manner as in Example 32, the title compound (620 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-25506b02fd7f465b88684dbd3cebc1c5 |
| Source note | uspto-grants-2014_08 |