化工社化工社 化学情報印刷レポート · 研究参考用
HCID 71251940、化合物 → HCID 71252335、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | HCID 71251940 | HCID 71251940 | — |
| 反応物 | (S)-4-methylisothiazolidine 1,1-dioxide | HCID 86676774 | — |
| 生成物 | HCID 71252335 | HCID 71252335 | 32.8% |
反応手順
Using (S)-4-methylisothiazolidine 1,1-dioxide (235 mg) described in Preparation Example 4 and [4-(3,5-dicyclopropylpyridin-2-yl)piperazin-1-yl](2-fluoro-4-iodophenyl)methanone (570 mg) described in Preparation Example 164 and by the reaction and treatment in the same manner as in Example 1, the title compound (190 mg) was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08816079B2 |
| 出典データセット | uspto-grants-2014_08 |
| ORD ID | ord-fc4599ca30684e83840c3540305cf617 |
| 出典メモ | uspto-grants-2014_08 |