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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411429Generated: November 2, 2026

(4-Iodophenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone → HCID 71252168, compound

https://huagongshe.com/reaction/2411429

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Iodophenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484793—
Reactant(S)-4-methylisothiazolidine 1,1-dioxideHCID 86676774—
ProductHCID 71252168HCID 7125216855%

Reaction Steps

Using (S)-4-methylisothiazolidine 1,1-dioxide (90 mg) described in Preparation Example 4 and (4-iodophenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone (193 mg) described in Preparation Example 120 and by the reaction and treatment in the same manner as in Example 4, the title compound (108 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-a61426260e284f2a8afb7ef3166e6570
Source noteuspto-grants-2014_08