HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-3-benzyloxymethylisothiazolidine 1,1-dioxide → HCID 71252868, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-3-benzyloxymethylisothiazolidine 1,1-dioxide | HCID 16664117 | — |
| Reactant | [4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone | HCID 58484841 | — |
| Product | HCID 71252868 | HCID 71252868 | 37.9% |
Reaction Steps
Using (S)-3-benzyloxymethylisothiazolidine 1,1-dioxide (241 mg) described in Preparation Example 1 and [4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone (447 mg) described in Preparation Example 117 and by the reaction and treatment in the same manner as in Example 32, the title compound (178 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-09a3b385d12544bcafa66f801c376fb8 |
| Source note | uspto-grants-2014_08 |