HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-3-methylisothiazolidine 1,1-dioxide → HCID 71252270, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-3-methylisothiazolidine 1,1-dioxide | HCID 16664802 | — |
| Reactant | HCID 71252509 | HCID 71252509 | — |
| Product | HCID 71252270 | HCID 71252270 | 55.8% |
Reaction Steps
Using (2,6-difluoro-4-iodophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (743 mg) described in Preparation Example 158 and (R)-3-methylisothiazolidine 1,1-dioxide (220 mg) described in Preparation Example 2 and by the reaction and treatment in the same manner as in Example 1, the title compound (421 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-16d14fa961b646a8b6de81661e3d1cf4 |
| Source note | uspto-grants-2014_08 |