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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411548Generated: October 31, 2026

1-(3-Methyl-5-trifluoromethylpyridin-2-yl)piperazine → HCID 71251863, compound

https://huagongshe.com/reaction/2411548

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Methyl-5-trifluoromethylpyridin-2-yl)piperazineHCID 58484729—
Reactant4-(1,1-Dioxo-1lambda6-isothiazolidin-2-yl)-2-methanesulfonylbenzoic acidHCID 71252108—
ProductHCID 71251863HCID 7125186382.2%

Reaction Steps

Using 4-(1,1-dioxo-1λ6-isothiazolidin-2-yl)-2-methanesulfonylbenzoic acid (319 mg) described in Preparation Example 22 and 1-(3-methyl-5-trifluoromethylpyridin-2-yl)piperazine (245 mg) described in Preparation Example 84 and by the reaction and treatment in the same manner as in Example 87, the title compound (449 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-820947c999684dd1bf04cd1a51ed9f7c
Source noteuspto-grants-2014_08