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1-(3-Cyclopropyl-5-trifluoromethylpyridin-2-yl)piperazine → HCID 71252417、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(3-Cyclopropyl-5-trifluoromethylpyridin-2-yl)piperazine | HCID 58484772 | — |
| 反応物 | HCID 71252108 | HCID 71252108 | — |
| 生成物 | HCID 71252417 | HCID 71252417 | 79.5% |
反応手順
Using 4-(1,1-dioxo-1λ6-isothiazolidin-2-yl)-2-methanesulfonylbenzoic acid (319 mg) described in Preparation Example 22 and 1-(3-cyclopropyl-5-trifluoromethylpyridin-2-yl)piperazine (271 mg) described in Preparation Example 90 and by the reaction and treatment in the same manner as in Example 87, the title compound (455 mg) was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08816079B2 |
| 出典データセット | uspto-grants-2014_08 |
| ORD ID | ord-780f4f532eb94c648b2e7898e5ea3feb |
| 出典メモ | uspto-grants-2014_08 |