HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Cyclopropyl-5-methylpyridin-2-yl)piperazine → HCID 71252426, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Cyclopropyl-5-methylpyridin-2-yl)piperazine | HCID 58484621 | — |
| Reactant | ethyl (R)-2-methanesulfonyl-4-(3-methyl-1,1-dioxo-1lambda6-isothiazolidin-2-yl)benzoate | HCID 71261164 | — |
| Product | HCID 71252426 | HCID 71252426 | 75.7% |
Reaction Steps
Using ethyl (R)-2-methanesulfonyl-4-(3-methyl-1,1-dioxo-1λ6-isothiazolidin-2-yl)benzoate (181 mg) described in Preparation Example 28 and 1-(3-cyclopropyl-5-methylpyridin-2-yl)piperazine (109 mg) described in Preparation Example 86 and by the reaction and treatment in the same manner as in Example 109, the title compound (202 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-63d77e68be884e12ad54a088bda1db80 |
| Source note | uspto-grants-2014_08 |