HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Cyclopropyl-5-trifluoromethylpyridin-2-yl)piperazine → HCID 71252559, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Cyclopropyl-5-trifluoromethylpyridin-2-yl)piperazine | HCID 58484772 | — |
| Reactant | 2,4-Bis(1,1-dioxo-1lambda6-isothiazolidin-2-yl)benzoic acid | HCID 71252293 | — |
| Product | HCID 71252559 | HCID 71252559 | 47.2% |
Reaction Steps
Using 2,4-bis(1,1-dioxo-1λ6-isothiazolidin-2-yl)benzoic acid (200 mg) described in Preparation Example 34 and 1-(3-cyclopropyl-5-trifluoromethylpyridin-2-yl)piperazine (150 mg) described in Preparation Example 90 and by the reaction and treatment in the same manner as in Example 87, the title compound (160 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-3ff0675e6f324b1badaf76ef4c8c7b02 |
| Source note | uspto-grants-2014_08 |