1-(3,5-Dicyclopropylpyridin-2-yl)piperazine hydrochloride → [4-(3,5-Dicyclopropylpyridin-2-yl)piperazin-1-yl][4-(1,1-dioxo-1lambda6-isothiazolidin-2-yl)-2-methoxyphenyl]methanone

Participants

Reaction Steps

Using 4-(1,1-dioxo-1λ6-isothiazolidin-2-yl)-2-methoxybenzoic acid (271 mg) described in Preparation Example 19 and 1-(3,5-dicyclopropylpyridin-2-yl)piperazine hydrochloride (316 mg) described in Preparation Example 87 and by the reaction and treatment in the same manner as in Example 86, the title compound (347 mg) was obtained.

Provenance & Evidence