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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411609Generated: November 3, 2026

1-(2,4,5-Trimethylphenyl)piperazine → HCID 71252812, compound

https://huagongshe.com/reaction/2411609

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2,4,5-Trimethylphenyl)piperazineHCID 2760821—
ReactantEthyl 6-(1,1-dioxo-1lambda6-isothiazolidin-2-yl)nicotinateHCID 71251937—
ProductHCID 71252812HCID 7125281270.9%

Reaction Steps

Using ethyl 6-(1,1-dioxo-1λ6-isothiazolidin-2-yl)nicotinate (300 mg) described in Preparation Example 25 and 1-(2,4,5-trimethylphenyl)piperazine (249 mg) and by the reaction and treatment in the same manner as in Example 109, the title compound (337 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-b069a1a06fe4473ca1dcb01c7ab9b7ee
Source noteuspto-grants-2014_08