HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloropropanesulphonyl chloride → HCID 71252031, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloropropanesulphonyl chloride | HCID 15410 | — |
| Reactant | 4-Methoxybenzylamine | HCID 75452 | — |
| Reactant | HCID 71252217 | HCID 71252217 | — |
| Reactant | HCID 71252409 | HCID 71252409 | — |
| Product | HCID 71252031 | HCID 71252031 | — |
Reaction Steps
Using (6-fluoro-4-methylpyridin-3-yl)[4-(2,4,5-trimethylphenyl)piperazin-1-yl]methanone (310 mg) described in Preparation Example 180, 4-methoxybenzylamine (2 mL) and 3-chloropropane-1-sulfonyl chloride (0.23 mL) and by the reaction and treatment in the same manner as in Example 229, the title compound (185 mg) was obtained via (6-amino-4-methylpyridin-3-yl)[4-(2,4,5-trimethylphenyl)piperazin-1-yl]methanone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-3d7b3b21d4a9415c9b9094f4485f6ee3 |
| Source note | uspto-grants-2014_08 |