反应详情

Using 2-[4-(6-bromopyridine-3-carbonyl)piperazin-1-yl]-5-methylnicotinonitrile (150 mg) described in Preparation Example 184 and isothiazolidine 1,1-dioxide (71 mg) and by the reaction and treatment in the same manner as in Example 1, the title compound (114 mg) was obtained.