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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411647Generated: November 3, 2026

Methyl p-toluenesulfonate → HCID 71252828, compound

https://huagongshe.com/reaction/2411647

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl p-toluenesulfonateHCID 6645—
ReactantHCID 71251927HCID 71251927—
ProductHCID 71252828HCID 7125282827.7%

Reaction Steps

Using (S)-1-{4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]-3-methanesulfonylphenyl}-5-hydroxymethylpyrrolidin-2-one (530 mg) described in Example 274 and methyl tosylate (203 mg) and by the reaction and treatment in the same manner as in Example 36, the title compound (151 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-894ddeee476642fe88bd383504e3b693
Source noteuspto-grants-2014_08