HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyrrolidone → HCID 71251878, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Reactant | (4-Bromo-2-methanesulfonylphenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484505 | — |
| Product | HCID 71251878 | HCID 71251878 | 32.3% |
Reaction Steps
Using pyrrolidin-2-one (119 mg) and (4-bromo-2-methanesulfonylphenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (664 mg) described in Preparation Example 112 and by the reaction and treatment in the same manner as in Example 1, the title compound (206 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-a371c5f9981c4f2e9d44a3bd04dd2fe9 |
| Source note | uspto-grants-2014_08 |