HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-5-(Hydroxymethyl)-2-pyrrolidinone → HCID 71252589, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-5-(Hydroxymethyl)-2-pyrrolidinone | HCID 643511 | — |
| Reactant | (4-Iodophenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484793 | — |
| Product | HCID 71252589 | HCID 71252589 | — |
Reaction Steps
Using (S)-5-hydroxymethylpyrrolidin-2-one and (4-iodophenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone (871 mg) described in Preparation Example 120 and by the reaction and treatment in the same manner as in Example 1, the title compound (348 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-22d2b08294194230b8283aa2b4509fc3 |
| Source note | uspto-grants-2014_08 |