HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyrrolidone → HCID 71252636, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Reactant | [4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone | HCID 58484841 | — |
| Product | HCID 71252636 | HCID 71252636 | 60.9% |
Reaction Steps
Using pyrrolidin-2-one (94 mg) and [4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl](4-iodophenyl)methanone (447 mg) described in Preparation Example 117 and by the reaction and treatment in the same manner as in Example 1, the title compound (246 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-a0ad17524b794dd79ef293ab8290c4a6 |
| Source note | uspto-grants-2014_08 |