HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyrrolidone → HCID 71252958, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Reactant | (6-Bromopyridin-3-yl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484652 | — |
| Product | HCID 71252958 | HCID 71252958 | 55.9% |
Reaction Steps
Using pyrrolidin-2-one (49 mg) and (6-bromopyridin-3-yl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (200 mg) described in Preparation Example 145 and by the reaction and treatment in the same manner as in Example 1, the title compound (113 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-16821c6e55a644b4a3d9acf1d51b83fe |
| Source note | uspto-grants-2014_08 |