HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Hydroxymethyl)pyrrolidin-2-one → HCID 71252133, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Hydroxymethyl)pyrrolidin-2-one | HCID 558359 | — |
| Reactant | HCID 58484529 | HCID 58484529 | — |
| Product | HCID 71252133 | HCID 71252133 | 15% |
Reaction Steps
Using (4-bromo-2,6-difluorophenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone (819 mg) described in Preparation Example 109 and 5-hydroxymethylpyrrolidin-2-one (230 mg) and by the reaction and treatment in the same manner as in Example 1, the title compound (133 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-367432373b4e423b810e6c56b8d5fa84 |
| Source note | uspto-grants-2014_08 |