HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Acetylimidazolidinone → HCID 71252212, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Acetylimidazolidinone | HCID 79350 | — |
| Reactant | 5-Bromo-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile | HCID 58484573 | — |
| Product | HCID 71252212 | HCID 71252212 | 41.9% |
Reaction Steps
Using 5-bromo-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile (1.06 g) described in Preparation Example 189 and 1-acetylimidazolidin-2-one (384 mg) and by the reaction and treatment in the same manner as in Example 1, the title compound (494 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-5ac41636245b4496be2f3ea48dec02fb |
| Source note | uspto-grants-2014_08 |