HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Azetidinone → HCID 71252114, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Azetidinone | HCID 136721 | — |
| Reactant | (4-Bromo-2,6-difluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484761 | — |
| Product | HCID 71252114 | HCID 71252114 | 54.7% |
Reaction Steps
Using (4-bromo-2,6-difluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (410 mg) described in Preparation Example 111 and 2-azetidinone (75 mg) and by the reaction and treatment in the same manner as in Example 1, the title compound (219 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-f9a23722af9b44da9bfe8a51a6fabd13 |
| Source note | uspto-grants-2014_08 |