HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methylsulfonamido)benzoic acid → N-{4-[4-(4-methylbenzoyl)piperidine-1-carbonyl]phenyl}methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methylsulfonamido)benzoic acid | HCID 250653 | — |
| Reactant | 4-(4-Methylbenzoyl)piperidine hydrochloride | HCID 2740817 | — |
| Product | N-{4-[4-(4-methylbenzoyl)piperidine-1-carbonyl]phenyl}methanesulfonamide | HCID 71252640 | 14.6% |
Reaction Steps
Using 4-methanesulfonylaminobenzoic acid (136 mg) and (4-methylphenyl)(piperidin-4-yl)methanone hydrochloride (152 mg) and by the reaction and treatment in the same manner as in Example 86, the title compound (37 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-0dc2197c7baa4f018c7fd80ce95cdeea |
| Source note | uspto-grants-2014_08 |