HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylmethanesulfonamide → HCID 71252042, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylmethanesulfonamide | HCID 97632 | — |
| Reactant | (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484626 | — |
| Product | HCID 71252042 | HCID 71252042 | 89.5% |
Reaction Steps
Using (4-bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (624 mg) described in Preparation Example 114 and N-methylmethanesulfonamide (349 mg) and by the reaction and treatment in the same manner as in Example 4, the title compound (599 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-a73b88fabaf14b4c8ad1ce046dac07c9 |
| Source note | uspto-grants-2014_08 |