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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411880Generated: November 2, 2026

(4-Bromo-2-fluorophenyl)[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone → HCID 71252068, compound

https://huagongshe.com/reaction/2411880

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Bromo-2-fluorophenyl)[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484842—
Reactant1-(4-Methoxybenzyl)-4-methylimidazolidin-2-oneHCID 71252004—
ReactantHCID 71252942HCID 71252942—
ProductHCID 71252068HCID 71252068—

Reaction Steps

Using (4-bromo-2-fluorophenyl)[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (167 mg) described in Preparation Example 121 and 1-(4-methoxybenzyl)-4-methylimidazolidin-2-one (106 mg) described in Preparation Example 52 and by the reaction and treatment in the same manner as in Example 506, the title compound (109 mg) was obtained via 3-{4-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]-3-fluorophenyl}-1-(4-methoxybenzyl)-4-methylimidazolidin-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-537de29dc89b444f944e51d49e96832e
Source noteuspto-grants-2014_08