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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411898Generated: November 3, 2026

(4-Bromo-2-fluorophenyl) [4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone → HCID 71252015, compound

https://huagongshe.com/reaction/2411898

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Bromo-2-fluorophenyl) [4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484847—
Reactant3-(4-Methoxybenzyl)-5-methylimidazolidine-2,4-dioneHCID 68328356—
ReactantHCID 71252342HCID 71252342—
ProductHCID 71252015HCID 71252015—

Reaction Steps

Using (4-bromo-2-fluorophenyl)[4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone (325 mg) described in Preparation Example 128 and 3-(4-methoxybenzyl)-5-methylimidazolidine-2,4-dione (187 mg) described in Preparation Example 51 and by the reaction and treatment in the same manner as in Example 508, the title compound (169 mg) was obtained via 1-{3-fluoro-4-[4-(3,5,6-trimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}-3-(4-methoxybenzyl)-5-methylimidazolidine-2,4-dione.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-bffdb2eb8a1048f8a1afa7f0f366a6f7
Source noteuspto-grants-2014_08