HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol hydrochloride → HCID 71252528, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol hydrochloride | HCID 21887872 | — |
| Reactant | HCID 54675508 | HCID 54675508 | — |
| Solvent | Chloroform methanol | HCID 21584188 | — |
| Product | HCID 71252528 | HCID 71252528 | — |
Reaction Steps
1-{4-[4-(3,5-Dimethylpyridin-2-yl)piperazine-1-carbonyl]-3-fluorophenyl}imidazolidin-2-one (840 mg) described in Example 416 was dissolved in chloroform/methanol, 2N hydrogen chloride/ethanol solution was added, and the solvent was evaporated under reduced pressure. The obtained residue was suspension washed with ethyl acetate to give the title compound (909 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-0441c7e5aac8440bb8783c5cbe9bea55 |
| Source note | uspto-grants-2014_08 |