HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21700179, compound → HCID 71251908, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21700179 | HCID 21700179 | — |
| Reactant | (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484626 | — |
| Reactant | HCID 71252197 | HCID 71252197 | — |
| Product | HCID 71251908 | HCID 71251908 | — |
Reaction Steps
Using (4-bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (235 mg) described in Preparation Example 114 and 3-(4-methoxybenzyl)-5,5-dimethylimidazolidine-2,4-dione (149 mg) described in Preparation Example 53 and by the reaction and treatment in the same manner as in Example 508, the title compound (130 mg) was obtained via 1-{4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]-3-fluorophenyl}-3-(4-methoxybenzyl)-5,5-dimethylimidazolidine-2,4-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-40d0839b9f4e4f4b989a21d4f2a497b5 |
| Source note | uspto-grants-2014_08 |