HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Imidazolidinedione, 3-methyl- → HCID 71251872, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Imidazolidinedione, 3-methyl- | HCID 138851 | — |
| Reactant | (4-Bromo-2-fluorophenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484537 | — |
| Product | HCID 71251872 | HCID 71251872 | 65.2% |
Reaction Steps
Using (4-bromo-2-fluorophenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (163 mg) described in Preparation Example 211 and 3-methylimidazolidine-2,4-dione (68 mg) described in Preparation Example 214 and by the reaction and treatment in the same manner as in Example 536, the title compound (115 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-446873959fb24e1884145dca72d4597a |
| Source note | uspto-grants-2014_08 |