HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyrrolidone → HCID 71252377, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Reactant | HCID 58484546 | HCID 58484546 | — |
| Product | HCID 71252377 | HCID 71252377 | 44.8% |
Reaction Steps
Using 1-acetyl-3-{5-chloro-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]phenyl}imidazolidin-2-one (165 mg) described in Preparation Example 236 and pyrrolidin-2-one (44 mg) and by the reaction and treatment in the same manner as in Example 649, the title compound (75 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-94f0ac6ac7944fd9a806d20146e60171 |
| Source note | uspto-grants-2014_08 |