HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 71252189, compound → HCID 71252623, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 71252189 | HCID 71252189 | — |
| Solvent | Methylamine tetrahydrofuran | HCID 66615946 | — |
| Product | HCID 71252623 | HCID 71252623 | 65.7% |
Reaction Steps
Using N,N-di-tert-butyloxycarbonyl-5-(1,1-dioxo-1λ6-isothiazolidin-2-yl)-2-[4-(5-ethyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]benzamide (202 mg) described in Example 785 and 2 mol/L methylamine tetrahydrofuran solution (180 μL) and by the reaction and treatment in the same manner as in Example 770, the title compound (96 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-009927ad582f488db37c7bcb7b6f19f0 |
| Source note | uspto-grants-2014_08 |