HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-2-pyrrolidone → HCID 71252669, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-2-pyrrolidone | HCID 66055 | — |
| Reactant | 5-Bromo-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile | HCID 58484628 | — |
| Product | HCID 71252669 | HCID 71252669 | 92.3% |
Reaction Steps
Using 5-bromo-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile (1 g) described in Preparation Example 187 and 5-methylpyrrolidin-2-one (372 mg) and by the reaction and treatment in the same manner as in Example 262, the title compound (965 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-923fe5664bbf4b1f9cb671aa1cf4f08c |
| Source note | uspto-grants-2014_08 |