2-Amino-4,6-dimethyl pyrimidine → HCID 13135277, compound

Participants

Reaction Conditions

Reaction Steps

15.4 g (0.05 mole) of 2-chlorododecylsulfonyl isocyanate in 100 ml of dichloromethane were initially introduced and 6.2 g (0.05 mole) of 2-amino-4,6-dimethylpyrimidine were added in portions at 0° C. The mixture was initially stirred at 0° C. for 2 hours and then at room temperature for 18 hours and was then worked up in analogy to Example 5. 15.2 g (71% of theory) of N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-chlorocyclododecylsulfonamide were obtained (pale yellow solid material, melting point 84° C.).

Provenance & Evidence