2-Amino-4,6-dimethyl pyrimidine → HCID 20432160, compound

Participants

Reaction Conditions

Reaction Steps

14.1 g (0.06 mole) of 3-chlorobicyclo[2.2.1]hept-2-ylsulfonyl isocyanate in 100 ml of dichloromethane were initially introduced and 7.4 g (0.06 mole) of 2-amino-4,6-dimethylpyrimidine were added in portions at 0° C. The mixture was initially stirred at 0° C. for 2 hours and then at room temperature for 18 hours and then worked up in analogy to Example 5. 14.1 g (66% of theory) of N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-3-chlorobicyclo[2.2.1]hept-2-ylsulfonamide were obtained (viscous oil).

Provenance & Evidence