Sodium Bicarbonate → Naphthalen-1(2H)-one

HRID 2412444Notes

Reaction equation

HRID 2412444 reaction equation
Br.N1([CH:7]2[CH2:16][CH2:15][C:14]3[C:9](=[CH:10][CH:11]=[C:12](O)[CH:13]=3)[C:8]2=[O:18])C=CN=C1.C([O-])(O)=O.[Na+]>O>[C:8]1(=[O:18])[C:9]2[C:14](=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:15]=[CH:16][CH2:7]1

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 13135502HCID 13135502, compound

Product 1

HCID 12446728Naphthalen-1(2H)-one

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2-(1-imidazolyl)-3,4-dihydro-6-hydroxy-1(2H)-naphthalenone hydrobromide (1.35 g) was dissolved in water. The solution, basified with NaHCO3, extracted with CH2Cl2, dried and evaporated, gave 1.15 g of 2-(1-imidazolyl)-3,4-dihydro-6-hydroxy-1(2N)-naphthalenone.

Workup

  1. extractionextracted with CH2Cl2
  2. customdried
  3. customevaporated

Sources & evidence

ORD record
ord-380831f06d4b4b2bb189497e3bf8d27d
Source dataset
uspto-grants-1985_01
Patent number
US04492707

Reaction notes

Loading…