Pyridine → HCID 54032103, compound

HRID 2412505Notes

Reaction equation

HRID 2412505 reaction equation
[F:1][C:2]1[N:3]([C:9]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:4]=[C:5](C=O)[N:6]=1.Cl.[CH3:29][O:30][NH2:31].N1C=CC=CC=1>CCO>[F:1][C:2]1[N:3]([C:9]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH2:4][C:5](=[N:31][O:30][CH3:29])[N:6]=1

Participants

5

Reactant 3

HCID 1049PyridineHCID 521874O-Methylhydroxylamine hydrochlorideHCID 537790282-Fluoro-1-trityl-1H-imidazole-4-carbaldehyde

Product 1

HCID 54032103HCID 54032103, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Fluoro-4-formyl-1-triphenylmethylimidazole was reacted in EtOH with O-methylhydroxylamine hydrochloride and pyridine, to give 2-fluoro-4-methoxyimino-1-triphenylmethylimidazole, as a 3:1 mixture of geometrical isomers, having the following n.m.r. in CDCl3 : 3.87 (s, 0.75H); 3.93 (s, 0.25H); 7.05-7.5 (m, 17H).

Sources & evidence

ORD record
ord-b1553535361c4f728f78d0b90526845f
Source dataset
uspto-grants-1985_01
Patent number
US04492692

Reaction notes

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