Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2412517Generated: November 4, 2026

Butanoic acid, 4-chloro-, 1,1-dimethylethyl ester → 1-(3-t-Butoxycarbonylpropyl)-2-fluoroimidazole

https://huagongshe.com/reaction/2412517

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButanoic acid, 4-chloro-, 1,1-dimethylethyl esterHCID 527695—
Reactant2-Fluoro-1H-imidazoleHCID 559542—
Product1-(3-t-Butoxycarbonylpropyl)-2-fluoroimidazoleHCID 20432311—

Reaction Steps

2-Fluoroimidazole was alkylated with t-butyl-4-chlorobutyrate, using the same procedure as that for the starting material of Example 74, to give 1-(3-t-butoxycarbonylpropyl)-2-fluoroimidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04492692
Source datasetuspto-grants-1985_01
ORD IDord-83eb0b47c00549c18137d0c7ec7078f6
Source noteuspto-grants-1985_01