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HRID2412520

反应详情

EQUATION

反应方程式

HRID 2412520 的结构方程式

REACTANTS

反应物

2
结构：Fc1nc(CCl)cn1C(c1ccccc1)(c1ccccc1)c1ccccc1
HCID20432342

未命名化合物

结构：CC(C)(C)[O-].[C-]#[N+]CC(=O)OCC.[K+]
HCID86739866

未命名化合物

PRODUCTS

生成物

1
结构：[C-]#[N+]C(Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)n1)C(=O)OCC
HCID20432399

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

Reaction of 4-chloromethyl-2-fluoro-1-triphenylmethylimidazole with ethyl isocyanoacetate/potassium t-butoxide in THF followed by chromatography on silica gel gave 4-(2-ethoxycarbonyl-2-isocyanoethyl)-2-fluoro-1-triphenylmethylimidazole having the following n.m.r. in CDCl3 : 1.24 (t, 2H); 2.7-3.17 (d, 2H); 4.18 (q, 1H); 4.5 (dd, 1H); 6.4 (s, 1H); 7.0-7.4 (m, 15H).