HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Methylhydroxylamine → N-(5-tert-Butyl-1,2-oxazol-3-yl)-N'-methoxyurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Methylhydroxylamine | HCID 4113 | — |
| Reactant | 5-Tert-butyl-3-isocyanato-1,2-oxazole | HCID 12918838 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(5-tert-Butyl-1,2-oxazol-3-yl)-N'-methoxyurea | HCID 13370466 | — |
Reaction Steps
8.5 g of methoxyamine was added very slowly to a stirred solution of 15 g of 4A in 600 ml of tetrahydrofuran. The resulting mixture was filtered and the solid was triturated with ether to give 1-methoxy-3-(5-(tertiary-butyl)-1,2-oxazol-3-yl)urea (4B), m.p.: 145°-148° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04493728 |
| Source dataset | uspto-grants-1985_01 |
| ORD ID | ord-913f2808d8284d4d91ad6f7602ea6369 |
| Source note | uspto-grants-1985_01 |