HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 3062237, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1H-Indole, 3-(4-piperidinylmethyl)- (9CI) | HCID 19026 | — |
| Reactant | Tetrafluoro-m-phenylenediamine dihydrochloride | HCID 149026 | — |
| Catalyst | Benzyl triethylammonium chloride | HCID 66133 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 3062237 | HCID 3062237 | — |
Reaction Steps
The operation is as in Example 1, but starting from 13.4 g of 4-(3-indolyl-methyl)-piperidine and 0.54 g of triethylbenzylammonium chloride in 130 ml of chloroform and 19.5 g of sodium hydroxide in solution in 39 ml of water. 4.2 g of 3-chloro-4-[(4-piperidyl)-methyl]-quinoline are finally obtained in the form of the dihydrochloride melting above 260° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04493838 |
| Source dataset | uspto-grants-1985_01 |
| ORD ID | ord-b92e81efc7c7407ab4c6b1541f8273b5 |
| Source note | uspto-grants-1985_01 |