Hydrochloric Acid → HCID 12799926, compound

Participants

Reaction Steps

A solution of 2-(n-heptyl)indole-5-carboxylic acid (18.4 g) in ethanol (80 ml) containing a solution of hydrogen chloride gas in ethanol (110 ml, of strength 34% w/v) was refluxed for 6 hours. The solution was poured into water and the solid was collected and was recrystallised from methanol to give ethyl 2-(n-heptyl)indole-5-carboxylate (10.7 g), in the form of buff crystals, m.p. 66°-69° C.

Provenance & Evidence