HCID 5115132, compound → HCID 12797236, compound

HRID 2412622Notes

Reaction equation

HRID 2412622 reaction equation
[C:1]([NH:14][C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][C:23]=1[CH3:24])[C:18]([OH:20])=[O:19])(=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].CC(C)([O-])C.[K+]>CCN(C1C=CC=CC=1)CC>[CH2:2]([C:1]1[NH:14][C:15]2[C:23]([CH:24]=1)=[CH:22][CH:21]=[C:17]([C:18]([OH:20])=[O:19])[CH:16]=2)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

4

Reactant 2

HCID 5115132HCID 5115132, compoundHCID 23665647Potassium tert-butoxide

Product 1

HCID 12797236HCID 12797236, compoundYield 68.7%

Reagents, catalysts & solvents 1

HCID 7061N,N-DiethylanilineSolvent

Procedure

A mixture of 3-(n-dodecanamido)-4-methylbenzoic acid (4 g), potassium tert-butoxide (4 g) and diethylaniline (10 ml) was treated in a similar manner to that hereinbefore described in Example 83 to give 2-(n-undecyl)indole-6-carboxylic acid (2.6 g), m.p. 156°-158° C.

Workup

  1. additionwas treated in a similar manner to

Sources & evidence

ORD record
ord-22ed43f48a7c46299b18605da3209553
Source dataset
uspto-grants-1985_01
Patent number
US04493843

Reaction notes

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